The mystery of diabetes and atherosclerosis: time for a new plot.

Abstract

Most patients with diabetes die from macrovascular complications. Little is known about the pathogenesis of diabetic vascular disease, but recent advances in molecular genetics and oxidation chemistry provide clues to the mystery of diabetes and atherosclerosis. Genetic variants of well-known proteins such as lipoprotein lipase and apolipoprotein E are… (More)

W-S Yang, DDN Ncvin, R Peng, JD Brunzell, SS Deeb
Proc No I1 Auad Sci USA 92:446'2466, 1995
1996

P Benlian, JL De G e e s, L Foubert, H Zhang, SE Gagne, M Hayden
N Engl J Med
1996

The mystery of diabetes and atherosclerosis: time for a new plot.

Abstract

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Cited By

Effect of Dietary n − 3 Polyunsaturated Fatty Acids on Oxidant/Antioxidant Status in Macrosomic Offspring of Diabetic Rats

A modified simple method for determination of serum α-tocopherol (vitamin E).

Lipoprotein Lipase as a Candidate Target for Cancer Prevention/Therapy

Reduced Antioxidant Potential of LDL Is Associated With Increased Susceptibility to LDL Peroxidation in Type II Diabetic Patients

Mass spectrometric quantification of amino acid oxidation products identifies oxidative mechanisms of diabetic end-organ damage

Mechanisms for oxidative stress in diabetic cardiovascular disease.

Pancreatic B-cell function is altered by oxidative stress induced by acute hyperglycaemia

Diabetes mellitus worsens antioxidant status in patients with chronic pancreatitis.

Ultrastructural changes of pancreatic islets microcirculation in nonobese diabetic (NOD) mice.

Association between monocyte Fcγ subclass expression and acute coronary syndrome

References

A mutation in the pr* moter of the lipoprotein lipase (LF'L) gene in a pAent with familial combined hyperlipidemia and low LPL activity

Increased atherosclerosis in streptozotocin-induced diabetic mice.

Pre mature atherosclerosis in patients with hnilial chylornicronernia caused by mutations in the lipoprotein lipase gene

Prolonged postprandial responses of lipids and apolipoproteins in triglyceride-rich lipoproteins of individuals expressing an apolipoprotein epsilon 4 allele.

A lipoprotein lipase mutation (Asn291Ser) is associated with reduced HDL cholesterol levels in premature atherosclerosis

Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia.

Correction of hypertriglyceridemia with low high-density lipoprotein cholesterol by the novel compound NO-1886, a lipoprotein lipase-promoting agent, in STZ-induced diabetic rats.

Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene.

Essential amino acids regulate fatty acid synthase expression through an uncharged transfer RNA-dependent mechanism.

Exercise induces human lipoprotein lipase gene expression in skeletal muscle but not adipose tissue.

Slides referencing similar topics

The mystery of diabetes and atherosclerosis: time for a new plot.

Abstract

Topics

Figures and Tables

Cited By

Effect of Dietary n − 3 Polyunsaturated Fatty Acids on Oxidant/Antioxidant Status in Macrosomic Offspring of Diabetic Rats

A modified simple method for determination of serum α-tocopherol (vitamin E).

Lipoprotein Lipase as a Candidate Target for Cancer Prevention/Therapy

Reduced Antioxidant Potential of LDL Is Associated With Increased Susceptibility to LDL Peroxidation in Type II Diabetic Patients

Mass spectrometric quantification of amino acid oxidation products identifies oxidative mechanisms of diabetic end-organ damage

Mechanisms for oxidative stress in diabetic cardiovascular disease.

Pancreatic B-cell function is altered by oxidative stress induced by acute hyperglycaemia

Diabetes mellitus worsens antioxidant status in patients with chronic pancreatitis.

Ultrastructural changes of pancreatic islets microcirculation in nonobese diabetic (NOD) mice.

Association between monocyte Fcγ subclass expression and acute coronary syndrome

References

A mutation in the pr* moter of the lipoprotein lipase (LF'L) gene in a pAent with familial combined hyperlipidemia and low LPL activity

Increased atherosclerosis in streptozotocin-induced diabetic mice.

Pre mature atherosclerosis in patients with hnilial chylornicronernia caused by mutations in the lipoprotein lipase gene

Prolonged postprandial responses of lipids and apolipoproteins in triglyceride-rich lipoproteins of individuals expressing an apolipoprotein epsilon 4 allele.

A lipoprotein lipase mutation (Asn291Ser) is associated with reduced HDL cholesterol levels in premature atherosclerosis

Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia.

Correction of hypertriglyceridemia with low high-density lipoprotein cholesterol by the novel compound NO-1886, a lipoprotein lipase-promoting agent, in STZ-induced diabetic rats.

Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene.

Essential amino acids regulate fatty acid synthase expression through an uncharged transfer RNA-dependent mechanism.

Exercise induces human lipoprotein lipase gene expression in skeletal muscle but not adipose tissue.

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Slides referencing similar topics