The myofibroblast is the predominant plasminogen activator inhibitor-1-expressing cell type in human breast carcinomas.

@article{Offersen2003TheMI,
  title={The myofibroblast is the predominant plasminogen activator inhibitor-1-expressing cell type in human breast carcinomas.},
  author={Birgitte Vrou Offersen and Boye Schnack Nielsen and Gunilla H\oyer-Hansen and Fritz Rank and Stephen Jacques Hamilton-Dutoit and Jens Overgaard and Peter Andr{\'e} Andreasen},
  journal={The American journal of pathology},
  year={2003},
  volume={163 5},
  pages={1887-99}
}
The tumor level of plasminogen activator inhibitor-1 (PAI-1) is an informative biochemical marker of a poor prognosis in several cancer types. However, the tumor biological functions of PAI-1 and the identity of PAI-1-expressing cells are controversial. With the aim of immunohistochemically localizing PAI-1 in formalin-fixed, paraffin-embedded invasive… CONTINUE READING