The myoepithelial defense: a host defense against cancer.

  title={The myoepithelial defense: a host defense against cancer.},
  author={Mark D. Sternlicht and Sanford H. Barsky},
  journal={Medical hypotheses},
  volume={48 1},
The behavior of human tumors depends not only on the nature of the tumor cells themselves but also on the modifying effects of various normal host cells such as fibroblasts and endothelial cells. One cell type, however--the myoepithelial cell--has not been studied scientifically. Myoepithelial cells normally surround ducts and acini of glandular organs such as the breast and salivary glands and contribute to the synthesis of a surrounding basement membrane. This relationship suggests that… CONTINUE READING


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