The mycovirus CHV1 disrupts secretion of a developmentally regulated protein in Cryphonectria parasitica.

@article{Kamierczak2012TheMC,
  title={The mycovirus CHV1 disrupts secretion of a developmentally regulated protein in Cryphonectria parasitica.},
  author={Patryk Kaźmierczak and Patricia McCabe and Massimo Turina and Debora Jacob-Wilk and Neal K Van Alfen},
  journal={Journal of virology},
  year={2012},
  volume={86 11},
  pages={
          6067-74
        }
}
Infection of the chestnut blight fungus Cryphonectria parasitica with Cryphonectria hypovirus 1 (CHV1) causes disruption of virulence, pigmentation, and sporulation. Transcriptional downregulation of key developmentally regulated fungal genes occurs during infection, but vegetative growth is unaffected. Previous studies showed that CHV1 utilizes trans-Golgi network (TGN) secretory vesicles for replication. In this study, the fungal cell surface hydrophobin cryparin was chosen as a marker to… CONTINUE READING

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