The mutagenicity of saccharin impurities. I. Detection of mutagenic activity.

Abstract

Sodium saccharin, ortho-toluenesulfonamide and impurities extracted from commercially produced saccharin with water and organic solvents were tested for mutagenicity with strains of Salmonella typhimurium. The organic solvent soluble impurities exhibited strong mutagenic activity for TA98 and slight activity for TA100. Mutagenic activity for S. typhimurium… (More)

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@article{Stoltz1978TheMO, title={The mutagenicity of saccharin impurities. I. Detection of mutagenic activity.}, author={Daimen R Stoltz and B. Stavric and Robert D. Klassen and R D Bendall and Jonathan C Craig}, journal={Journal of environmental pathology and toxicology}, year={1978}, volume={1 1}, pages={139-46} }