The mushroom body defect gene product is an essential component of the meiosis II spindle apparatus in Drosophila oocytes.


In addition to their well-known effects on the development of the mushroom body, mud mutants are also female sterile. Here we show that, although the early steps of ovary development are grossly normal, a defect becomes apparent in meiosis II when the two component spindles fail to cohere and align properly. The products of meiosis are consequently… (More)

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