The muscle-hypertrophic effect of clenbuterol is additive to the hypertrophic effect of myostatin suppression.

Abstract

INTRODUCTION In this study we investigated the combined effect of myostatin (MSTN) suppression and β-agonist (clenbuterol) administration on muscle hypertrophy and the phosphorylation of muscle 4E-BP1 and p70S6k, two downstream effectors of the Akt/mTOR anabolic pathway. METHODS Female heterozygous MSTN-prodomain transgenic mice (an MSTN suppression model… (More)
DOI: 10.1002/mus.21950

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