The murine α1-Proteinase inhibitor gene family: Polymorphism, chromosomal location, and structure

@inproceedings{Barbour2002TheM,
  title={The murine α1-Proteinase inhibitor gene family: Polymorphism, chromosomal location, and structure},
  author={Karen W. Barbour and Fusheng Wei and Camilynn I. Brannan and Terence R. Flotte and Heinz Baumann and Franklin G. Berger},
  year={2002}
}
Abstract α 1 -Proteinase inhibitor (α 1 -PI) is a member of the serpin superfamily of serine proteinase inhibitors, which function in maintaining homeostasis through regulation of numerous proteolytic processes. In laboratory mice ( Mus musculus domesticus ), α 1 -PI occurs in multiple isoforms encoded by a family of three to five genes that are polymorphic among inbred strains and that are located at the Serpina1 locus on chromosome 12. In the present study, we have characterized the α 1 -PI… CONTINUE READING