The mummified Hodgkin cell: cell death in Hodgkin's disease.

@article{Lorenzen1997TheMH,
  title={The mummified Hodgkin cell: cell death in Hodgkin's disease.},
  author={Johann Lorenzen and Juergen Thiele and Robert Fischer},
  journal={The Journal of pathology},
  year={1997},
  volume={182 3},
  pages={288-98}
}
This study attempts to define more clearly the morphology and ultrastructure of mummified Hodgkin cells, to determine their incidence in the different histological subtypes of Hodgkin's disease (HD), and to correlate these data with the expression of p53, bcl-2, mdm2, and p21/WAF1. Forty-five cases of primary HD were examined at light and electron microscopic level. DNA strand breaks were detected by the in situ end-labelling (ISEL) and the TdT-mediated dUTP-digoxigenin nick end-labelling… CONTINUE READING
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