The multiple roles of PtdIns(4)P -- not just the precursor of PtdIns(4,5)P2.

@article{DAngelo2008TheMR,
  title={The multiple roles of PtdIns(4)P -- not just the precursor of PtdIns(4,5)P2.},
  author={Giovanni D'Angelo and Mariella Vicinanza and Antonella Di Campli and Maria Antonietta De Matteis},
  journal={Journal of cell science},
  year={2008},
  volume={121 Pt 12},
  pages={1955-63}
}
The phosphoinositides (PIs) are membrane phospholipids that actively operate at membrane-cytosol interfaces through the recruitment of a number of effector proteins. In this context, each of the seven different PI species represents a topological determinant that can establish the nature and the function of the membrane where it is located. Phosphatidylinositol 4-phosphate (PtdIns(4)P) is the most abundant of the monophosphorylated inositol phospholipids in mammalian cells, and it is produced… CONTINUE READING
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