The multiple functions of the thiol-based electron flow pathways of Escherichia coli: Eternal concepts revisited.

@article{VlamisGardikas2008TheMF,
  title={The multiple functions of the thiol-based electron flow pathways of Escherichia coli: Eternal concepts revisited.},
  author={Alexios Vlamis-Gardikas},
  journal={Biochimica et biophysica acta},
  year={2008},
  volume={1780 11},
  pages={1170-200}
}
Electron flow via thiols is a theme with many variations in all kingdoms of life. The favourable physichochemical properties of the redox active couple of two cysteines placed in the optimised environment of the thioredoxin fold allow for two electron transfers in between top biological reductants and ultimate oxidants. The reduction of ribonucleotide reductases by thioredoxin and thioredoxin reductase of Escherichia coli (E. coli) was one of the first pathways to be elucidated. Diverse… CONTINUE READING

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