The multifactorial basis for hypocalcemia during sepsis. Studies of the parathyroid hormone-vitamin D axis.

@article{Zaloga1987TheMB,
  title={The multifactorial basis for hypocalcemia during sepsis. Studies of the parathyroid hormone-vitamin D axis.},
  author={Gary P. Zaloga and B Chernow},
  journal={Annals of internal medicine},
  year={1987},
  volume={107 1},
  pages={36-41}
}
To learn about the pathogenesis of sepsis-associated hypocalcemia, we measured serum ionized calcium concentrations in 60 critically ill patients with bacterial sepsis; 12 (20%) had hypocalcemia. The mortality rate in the hypocalcemic patients with sepsis (50%) was higher than that in the normocalcemic patients with sepsis (29%). Only patients with gram-negative sepsis became hypocalcemic, and hypocalcemia contributed to hypotension in 7 of the 12 hypocalcemic patients. Serum calcium… CONTINUE READING

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Hypocalcemia during sepsis occurred in previously normocalcemic patients and was multifactorial in origin , resulting from acquired parathyroid gland insufficiency , renal 1 alpha - hydroxylase insufficiency , vitamin D deficiency , and acquired calcitriol resistance .
To learn about the pathogenesis of sepsis - associated hypocalcemia , we measured serum ionized calcium concentrations in 60 critically ill patients with bacterial sepsis ; 12 ( 20% ) had hypocalcemia .
To learn about the pathogenesis of sepsis - associated hypocalcemia , we measured serum ionized calcium concentrations in 60 critically ill patients with bacterial sepsis ; 12 ( 20% ) had hypocalcemia .
HypocalcemiaMay be treated byCalcitriol
Hypocalcemia during sepsis occurred in previously normocalcemic patients and was multifactorial in origin , resulting from acquired parathyroid gland insufficiency , renal 1 alpha - hydroxylase insufficiency , vitamin D deficiency , and acquired calcitriol resistance .
To learn about the pathogenesis of sepsis - associated hypocalcemia , we measured serum ionized calcium concentrations in 60 critically ill patients with bacterial sepsis ; 12 ( 20% ) had hypocalcemia .
To learn about the pathogenesis of sepsis - associated hypocalcemia , we measured serum ionized calcium concentrations in 60 critically ill patients with bacterial sepsis ; 12 ( 20% ) had hypocalcemia .
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