The multifaceted cardiac sodium channel and its clinical implications

@article{Chockalingam2012TheMC,
  title={The multifaceted cardiac sodium channel and its clinical implications},
  author={P. Chockalingam and A. Wilde},
  journal={Heart},
  year={2012},
  volume={98},
  pages={1318 - 1324}
}
  • P. Chockalingam, A. Wilde
  • Published 2012
  • Medicine
  • Heart
  • Sudden cardiac death (SCD), defined as death from a cardiac cause occurring shortly after the onset of symptoms, is most often due to an organic cardiac abnormality such as coronary artery disease or structural heart disease.1 However, death in young, active and previously healthy individuals with no identifiable cause on postmortem examination, termed sudden unexplained death (SUD), constitutes about 5% of SCD. When sudden death of unknown aetiology occurs in a child below 1 year of age, it is… CONTINUE READING
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    References

    SHOWING 1-10 OF 30 REFERENCES
    Cardiac ion channel mutations in the sudden infant death syndrome.
    • 78
    Genetic basis and molecular mechanism for idiopathic ventricular fibrillation
    • 1,671
    Postmortem molecular screening in unexplained sudden death.
    • 170
    Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A).
    • 474
    • PDF
    Phenotypical Manifestations of Mutations in the Genes Encoding Subunits of the Cardiac Sodium Channel
    • 193
    • Highly Influential
    SCN5A Mutation Associated With Dilated Cardiomyopathy, Conduction Disorder, and Arrhythmia
    • 411
    • PDF