The multifaceted adult epidermal stem cell.

  title={The multifaceted adult epidermal stem cell.},
  author={Laure Gambardella and Yann Barrandon},
  journal={Current opinion in cell biology},
  volume={15 6},
Adult epidermal stem cells renew the epithelial compartment of the skin throughout life and are the most accessible of all adult stem cells. Most importantly, epidermal stem cells can be efficiently cultivated and transplanted, a significant advantage for cell and gene therapy. Recent work has pointed to the hair follicle as the main repository of multipotent stem cells in skin. Hair follicles, which are often affected in the mouse by spontaneous or man-made mutations, have become superb model… CONTINUE READING

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