The mucosal vascular addressin is a tissue-specific endothelial cell adhesion molecule for circulating lymphocytes

@article{Nakache1989TheMV,
  title={The mucosal vascular addressin is a tissue-specific endothelial cell adhesion molecule for circulating lymphocytes},
  author={Maurice Nakache and Ellen Lakey Berg and Philip R. Streeter and Eugene C. Butcher},
  journal={Nature},
  year={1989},
  volume={337},
  pages={179-181}
}
Tissue position-dependent or address-dependent expression of cell adhesion molecules has been proposed to play a part in cellular positioning in a variety of systems, for example during neural development, the metastasis of neoplasms, and the tissue-specific homing of lymphocytes. The extravasation of blood-borne lymphocytes is regulated by interactions with the endothelium of specialised venules, such as the high endothelial venules (HEY) in organized lymph nodes and mucosal lymphoid tissues1… CONTINUE READING
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