The movement protein gene is involved in the virus-specific requirement of the coat protein in cell-to-cell movement of bromoviruses

@article{Sasaki2003TheMP,
  title={The movement protein gene is involved in the virus-specific requirement of the coat protein in cell-to-cell movement of bromoviruses},
  author={Nobumitsu Sasaki and Misao Arimoto and Hironori Nagano and Masashi Mori and Masanori Kaido and Kazuyuki Mise and Tetsuro Okuno},
  journal={Archives of Virology},
  year={2003},
  volume={148},
  pages={803-812}
}
 Brome mosaic virus (BMV) requires the coat protein (CP) for cell-to-cell movement whereas Cowpea chlorotic mottle virus (CCMV), from the same genus, does not. Chimeric viruses created by exchanging the movement protein (MP) gene between the viruses can move from cell to cell. We show that interference in CP expression impaired the movement of the chimeric CCMV with the BMV MP gene but not of the chimeric BMV with the CCMV MP gene. We thus conclude that the MP gene plays a crucial role in… CONTINUE READING
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