The mouse neurotrophin receptor trkB gene is transcribed from two different promoters.

@article{Barettino1999TheMN,
  title={The mouse neurotrophin receptor trkB gene is transcribed from two different promoters.},
  author={Domingo Barettino and Pedro M. Pombo and Gemma Espliguero and Angeles Rodr{\'i}guez-Pe{\~n}a},
  journal={Biochimica et biophysica acta},
  year={1999},
  volume={1446 1-2},
  pages={
          24-34
        }
}
We have analysed a 7-kb region upstream of the mouse trkB coding sequence. The region showed promoter activity in transient transfection experiments and conferred tissue-specific expression to a reporter gene. Deletion analysis of this region demonstrated the presence of two alternative promoters named P1 and P2 that have been mapped by RNase protection. P1 has been located to 1.8 kb and P2 to 0.5 kb upstream of the trkB translation start site. From the P1 promoter, alternative splicing… CONTINUE READING
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