The mouse in safety evaluation.

  • James A. Doull
  • Published 1987 in
    Archives of toxicology. Supplement. = Archiv fur…


Several recent publications have reviewed the history, rationale and experience concerning the use of mice as a test species in oncogenicity bioassay programs. Conclusions from three of these publications will be discussed: The Report of the International Expert Advisory Committee on the Relevance of Mouse Liver Hepatoma to Human Carcinogenic Risk (from the… (More)


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