The mouse communal nest: Investigating the epigenetic influences of the early social environment on brain and behavior development

@article{Branchi2009TheMC,
  title={The mouse communal nest: Investigating the epigenetic influences of the early social environment on brain and behavior development},
  author={Igor Branchi},
  journal={Neuroscience \& Biobehavioral Reviews},
  year={2009},
  volume={33},
  pages={551-559}
}
  • I. Branchi
  • Published 1 April 2009
  • Biology, Psychology
  • Neuroscience & Biobehavioral Reviews
View on Elsevier
doi.org
145 Citations
Highly Influential Citations
8
Background Citations
71
Methods Citations
3
Results Citations
2

Figures and Tables from this paper

145 Citations

Citation Type

Citation Type

The richness of social stimuli shapes developmental trajectories: Are laboratory mouse pups impoverished?
Shaping brain development: Mouse communal nesting blunts adult neuroendocrine and behavioral response to social stress and modifies chronic antidepressant treatment outcome
Early interactions with mother and peers independently build adult social skills and shape BDNF and oxytocin receptor brain levels
Birth spacing in the mouse communal nest shapes adult emotional and social behavior
Early social enrichment provided by communal nest increases resilience to depression-like behavior more in female than in male mice
Social Enrichment during Postnatal Development Induces Transgenerational Effects on Emotional and Reproductive Behavior in Mice
TLDR
Analysis of neuropeptide receptor levels suggest that a communal rearing environment may exert sustained effects on behavior through modification of oxytocin and vasopressin (V1a) receptor densities.
Communal nesting exerts epigenetic influences on affective and social behaviors in rats selectively bred for an infantile trait
Early social enrichment affects responsiveness to different social cues in female mice
Epigenetic modifications induced by early enrichment are associated with changes in timing of induction of BDNF expression
Chapter 10 Epigenetic Influence of the Social Environment
TLDR
There is emerging evidence supporting the hypothesis that epigenetic changes, such as DNA methylation and histone modifications, may mediate the effects of early life variations in the social interactions between mothers and infants and that the social experiences of juveniles and adults may also induce epigenetic change.
...
...

References

SHOWING 1-10 OF 143 REFERENCES
Communal nesting, an early social enrichment, affects social competences but not learning and memory abilities at adulthood
Communal nesting, an early social enrichment, increases the adult anxiety-like response and shapes the role of social context in modulating the emotional behavior
Early Social Enrichment Shapes Social Behavior and Nerve Growth Factor and Brain-Derived Neurotrophic Factor Levels in the Adult Mouse Brain
Early social enrichment augments adult hippocampal BDNF levels and survival of BrdU‐positive cells while increasing anxiety‐ and “depression”‐like behavior
TLDR
Findings show that CN, an highly stimulating early social environment, increases adult neuronal plasticity, as suggested by high BDNF levels and augmented number of newly generated cells in the hippocampus, which is associated to an increased anxiety‐ and “depression”‐like behavior.
The developmental psychobiology of behavioural plasticity in mice: the role of social experiences in the family unit
Long-term neurobehavioural impact of the postnatal environment in rats: manipulations, effects and mediating mechanisms
Epigenetic mechanisms mediating the long-term effects of maternal care on development
Long-term effects of the periadolescent environment on exploratory activity and aggressive behaviour in mice: social versus physical enrichment
Maternal care as a model for experience-dependent chromatin plasticity?
Early life stress as a risk factor for mental health: Role of neurotrophins from rodents to non-human primates
...
...