The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon-skipped transcript in meiosis.

@article{Habu1996TheMA,
  title={The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon-skipped transcript in meiosis.},
  author={T. Habu and T. Taki and A. West and Y. Nishimune and T. Morita},
  journal={Nucleic acids research},
  year={1996},
  volume={24 3},
  pages={
          470-7
        }
}
  • T. Habu, T. Taki, +2 authors T. Morita
  • Published 1996
  • Medicine, Biology
  • Nucleic acids research
  • Genetic recombination in meiosis plays an important role in generating diversity of genetic information. In yeast an Escherichia coli RecA-like gene, DMC1, is expressed in meiotic prophase and its product co-localizes with Rad51 protein on zygotene chromosomes. We have cloned the mouse and human homologs of the yeast DMC1 gene. The predicted human and mouse DMC1 proteins showed 54.1% sequence identity with yeast Dmc1 protein. The domain II region, highly conserved in the E.coli RecA-like… CONTINUE READING
    169 Citations
    Molecular cloning and characterization of RAD51-like genes from Arabidopsis thaliana
    • 65
    Identification of a novel human RAD51 homolog, RAD51B.
    • 136
    The Drosophila spn-D gene encodes a RAD51C-like protein that is required exclusively during meiosis.
    • 81
    • Highly Influenced
    • PDF

    References

    SHOWING 1-10 OF 65 REFERENCES
    A mouse homolog of the Escherichia coli recA and Saccharomyces cerevisiae RAD51 genes.
    • 160
    • PDF
    Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes.
    • 572
    • PDF
    Nucleotide sequence and promoter analysis of SPO13, a meiosis-specific gene of Saccharomyces cerevisiae.
    • 78
    • PDF