The mouse X chromosome is enriched for multi-copy testis genes exhibiting post-meiotic expression

@inproceedings{Mueller2008TheMX,
  title={The mouse X chromosome is enriched for multi-copy testis genes exhibiting post-meiotic expression},
  author={Jacob L. Mueller and Shantha K Mahadevaiah and Peter J. Park and Peter E. Warburton and David C. Page and James M A Turner},
  booktitle={Nature Genetics},
  year={2008}
}
According to the prevailing view, mammalian X chromosomes are enriched in spermatogenesis genes expressed before meiosis and deficient in spermatogenesis genes expressed after meiosis. The paucity of postmeiotic genes on the X chromosome has been interpreted as a consequence of meiotic sex chromosome inactivation (MSCI)—the complete silencing of genes on the XY bivalent at meiotic prophase. Recent studies have concluded that MSCI-initiated silencing persists beyond meiosis and that most genes… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Topics from this paper.
75 Citations
22 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 75 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 22 references

Similar Papers

Loading similar papers…