The mouse Pgk-1 gene promoter contains an upstream activator sequence.

@article{McBurney1991TheMP,
  title={The mouse Pgk-1 gene promoter contains an upstream activator sequence.},
  author={Michael W McBurney and Leslie C Sutherland and Chaker N. Adra and Beno{\^i}t Leclair and Michael Rudnicki and Karen Jardine},
  journal={Nucleic acids research},
  year={1991},
  volume={19 20},
  pages={5755-61}
}
The Pgk-1 gene encodes the housekeeping enzyme, 3-phosphoglycerate kinase, and is ubiquitously expressed. This gene resides on the X chromosome in mammals and is always expressed except where it is silenced along with most other genes on the inactive X chromosome of female somatic cells or male germ cells. The Pgk-1 promoter is in a region rich in nucleotides G and C. This promoter can efficiently drive high levels of expression of reporter genes such as E. coli lacZ and neo. We have determined… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
47 Extracted Citations
3 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 47 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-3 of 3 references

Cell culture methods and induction of differentiation of embryonal carcinoma cell lines. In: Teratocarcinomas and embryonic stem cells, a practical approach, edited by Robertson, E

  • M. A. Rudnicki, M. W. McBurney
  • J. Oxford: IRL Press,
  • 1987

Cell culture methods and induction of differentiation of embryonal carcinoma cell lines

  • M. A. Rudnicki, M. W. McBurney
  • Dev . Biol .
  • 1982

Molecular cloning: a laboratory manual, Cold Spring Harbor, New York:Cold

  • T Maniatis, T. Fritsch, J. Sambrook
  • Spring Harbor Laboratory,
  • 1982

Similar Papers

Loading similar papers…