The mouse Ms6-hm hypervariable microsatellite forms a hairpin and two unusual tetraplexes.

@article{Weitzmann1998TheMM,
  title={The mouse Ms6-hm hypervariable microsatellite forms a hairpin and two unusual tetraplexes.},
  author={M N Weitzmann and Kerry J Woodford and Karen Usdin},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 46},
  pages={30742-9}
}
The mouse Ms6-hm microsatellite consists of a tandem array of the pentamer d(CAGGG)n. This microsatellite is extremely hypervariable, showing a germ line mutation rate of 2.5%/gamete. The mechanism responsible for this instability is not known. The ability to form intrastrand structures is a conserved feature of many hypervariable sequences, and it has been suggested that the formation of such structures might account for instability by affecting DNA replication, repair, or recombination. Here… CONTINUE READING
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