The motility-proliferation-metabolism interplay during metastatic invasion

  title={The motility-proliferation-metabolism interplay during metastatic invasion},
  author={Inbal Hecht and Sari Natan and Assaf Zaritsky and Herbert Levine and Ilan Tsarfaty and Eshel Ben-Jacob},
  booktitle={Scientific reports},
Metastasis is the major cause for cancer patients' death, and despite all the recent advances in cancer research it is still mostly incurable. Understanding the mechanisms that are involved in the migration of the cells in a complex environment is a key step towards successful anti-metastatic treatment. Using experimental data-based modeling, we focus on the fundamentals of metastatic invasion: motility, invasion, proliferation and metabolism, and study how they may be combined to maximize the… CONTINUE READING

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