The morphogenetic MreBCD proteins of Escherichia coli form an essential membrane-bound complex.

@article{Kruse2005TheMM,
  title={The morphogenetic MreBCD proteins of Escherichia coli form an essential membrane-bound complex.},
  author={Thomas Kruse and Jette Bork-Jensen and Kenn Gerdes},
  journal={Molecular microbiology},
  year={2005},
  volume={55 1},
  pages={78-89}
}
MreB proteins of Escherichia coli, Bacillus subtilis and Caulobacter crescentus form actin-like cables lying beneath the cell surface. The cables are required to guide longitudinal cell wall synthesis and their absence leads to merodiploid spherical and inflated cells prone to cell lysis. In B. subtilis and C. crescentus, the mreB gene is essential. However, in E. coli, mreB was inferred not to be essential. Using a tight, conditional gene depletion system, we systematically investigated… CONTINUE READING
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