The morbidity of Clostridium difficile infection after elective colonic resection-results from a national population database.

@article{Lesperance2011TheMO,
  title={The morbidity of Clostridium difficile infection after elective colonic resection-results from a national population database.},
  author={Kelly E Lesperance and Marlin Wayne Causey and Michael Spencer and Scott Russell Steele},
  journal={American journal of surgery},
  year={2011},
  volume={201 2},
  pages={141-8}
}
BACKGROUND Clostridium difficile (CD), a gram-positive rod bacterium, resides normally within the human colon. Antibiotic treatment alters normal colonic flora, potentiating abnormal overgrowth of CD. METHODS This study examined the 2004 to 2006 Nationwide Inpatient Sample to determine outcomes of CD colitis after 695,010 elective colonic resections. RESULTS CD infection, occurring in 1.4% of patients, was associated with higher pulmonary (12.1% vs 6.4%) and gastrointestinal (12.8% vs 10.5… CONTINUE READING

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