The mononuclear phagocyte system revisited.

  title={The mononuclear phagocyte system revisited.},
  author={David A Hume and Ian L Ross and Stewart R Himes and R Tedjo Sasmono and Christine A. Wells and Timothy Ravasi},
  journal={Journal of leukocyte biology},
  volume={72 4},
  • David A Hume, Ian L Ross, +3 authors Timothy Ravasi
  • Published 2002 in Journal of leukocyte biology
The mononuclear phagocyte system (MPS) was defined as a family of cells comprising bone marrow progenitors, blood monocytes, and tissue macrophages. In this review, we briefly consider markers for cells of this lineage in the mouse, especially the F4/80 surface antigen and the receptor for macrophage colony-stimulating factor. The concept of the MPS is challenged by evidence that there is a separate embryonic phagocyte lineage, the blurring of the boundaries between macrophages and other cells… CONTINUE READING
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