The monocyte-macrophage axis in the intestine

  title={The monocyte-macrophage axis in the intestine},
  author={Calum C Bain and Allan McI Mowat},
  booktitle={Cellular immunology},
Macrophages are one of the most abundant leucocytes in the intestinal mucosa where they are essential for maintaining homeostasis. However, they are also implicated in the pathogenesis of disorders such as inflammatory bowel disease (IBD), offering potential targets for novel therapies. Here we discuss the function of intestinal monocytes and macrophages during homeostasis and describe how these populations and their functions change during infection and inflammation. Furthermore, we review the… CONTINUE READING
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