The monoamine hypothesis for the pathophysiology of paraphilic disorders: an update.

@article{Kafka2003TheMH,
  title={The monoamine hypothesis for the pathophysiology of paraphilic disorders: an update.},
  author={Martin P. Kafka},
  journal={Annals of the New York Academy of Sciences},
  year={2003},
  volume={989},
  pages={86-94; discussion 144-53}
}
  • Martin P. Kafka
  • Published 2003 in Annals of the New York Academy of Sciences
A monoamine hypothesis for the pathophysiology of paraphilic disorders was first articulated in 1997 by Kafka. This hypothesis was based on four converging lines of empirical evidence. First, the monoamine neurotransmitters, dopamine, norepinephrine, and serotonin serve a modulatory role in human and mammalian sexual motivation, appetitive, and consummatory behavior. Second, the sexual effects of pharmacological agents that affect monoamine neurotransmitters can have both significant… CONTINUE READING

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