The molecular structure and vibrational, (1)H and (13)C NMR spectra of lidocaine hydrochloride monohydrate.

  title={The molecular structure and vibrational, (1)H and (13)C NMR spectra of lidocaine hydrochloride monohydrate.},
  author={Hassan M. Badawi and Wolfgang F{\"o}rner and Shaikh A. Ali},
  journal={Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy},

Re-refinement of Crystal Structure of Bis(Lidocaine) Diaquatetrathiocyanatonickelate(II)

This paper reports on the synthesis and structure re-refinement of bis(lidocaine) diaquatetrathiocyanatonickelate(II). The compound with the formula (LidH)2[Ni(NCS)4(H2O)2], where Lid is

Mechanisms and pharmaceutical consequences of processes of stereoisomerisation - A didactic excursion.

  • B. TestaG. VistoliA. Pedretti
  • Chemistry
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
  • 2016

Lidocaine Pharmaceutical Multicomponent Forms: A Story about the Role of Chloride Ions on Their Stability

In this investigation, three new crystal forms of lidocaine, and another three of lidocaine hydrochloride with hydroquinone, resorcinol, and pyrogallol were synthetised. All the new forms were

Shape-selective separation of geraniol and nerol via noncovalent interactionswith β-cyclodextrin

Abstract In this paper, selective separation of the isomeric compounds geraniol and nerol, based on the preferential affinity of β-cyclodextrin (β-CD) for geraniol was investigated. To demonstrate

Prospective comparative study of the effects of lidocaine on urodynamic and sensory parameters in bladder pain syndrome

Lidocaine significantly improved MCC in 11/16 participants in this study, implying that in this subgroup, a peripheral drive from the bladder is not critical to their pain, suggesting central nervous system (CNS) pathology.

The role of inflammatory mediators in the overactive and bladder pain syndromes

The role of inflammatory mediators in the overactive and bladder pain syndromes is studied to help clarify the role of ‘silent’ and ‘active’ cytokines in these disorders.

Association of capsaicin with local anesthetics to increase analgesia : Associação de capsaicina com anestésicos locais para aumento da analgesia

The analgesic effect of a drug combination (LA and CAP) on inflamed tissue is reported for the first time and a parenteral formulation was developed that achieved desirable anesthesia effect, despite the inflammatory condition.



Application of solid-state 35Cl NMR to the structural characterization of hydrochloride pharmaceuticals and their polymorphs.

The sensitivity of the chlorine NMR interaction tensor parameters to the chlorine chemical environment and the potential for modeling these sites with ab initio calculations hold much promise for application to polymorph screening for a wide variety of HCl pharmaceuticals.

Theoretical vibrational spectra of cyclohexanecarboxaldehyde

Abstract. Vibrational spectra of cyclohexanecarboxaldehyde are calculated with density functional theory using the B3LYP functional together with a 6-311++G** basis set and presented. The results in

Molecular orbital theory of the electronic structure of organic compounds. I. Substituent effects and dipole moments.

A recent approximate self-consistent molecular orbital theory (complete neglect of differential overlap or CNDO) is used to calculate charge distributions and electronic dipole moments of a series of simple organic molecules, suggesting that charge alternation may be an intrinsic property of all induction and mesomeric electronic displacements.

Hydrogen bonding in lidocaine salts. I. The stretching band and its dependence on the associated anion

By means of deuterium exchange, the band was identified in a series of lidocaine salts with varying anionic size. A value for the free stretching frequency was obtained which permitted to be related

Charge at the lidocaine binding site residue Phe‐1759 affects permeation in human cardiac voltage‐gated sodium channels

Results demonstrate that permeation rate is sensitive to the inner pore electrostatic field, and they are consistent with creation of an electrostatic barrier to ion permeation by lidocaine's charge.

2‐(Diethyl­amino)‐N‐(2,6‐dimethyl­phenyl)acetamide, a low‐temperature redetermination

The title compound, commonly known as lidocaine, C14H22N2O, is a well known drug with local anaesthetic and anti-arrhythmic properties. Its structure has been reported previously, based on data of