The molecular signature of impaired diabetic wound healing identifies serpinB3 as a healing biomarker

@article{Fadini2014TheMS,
  title={The molecular signature of impaired diabetic wound healing identifies serpinB3 as a healing biomarker},
  author={Gian Paolo Fadini and Mattia Albiero and Renato Millioni and Nicol Poncina and Mauro Rigato and Rachele Scotton and Federico Boscari and Enrico Brocco and G. Arrigoni and Gianmarco Villano and Cristian Turato and Alessandra Biasiolo and Patrizia Pontisso and Angelo Avogaro},
  journal={Diabetologia},
  year={2014},
  volume={57},
  pages={1947-1956}
}
Chronic foot ulceration is a severe complication of diabetes, driving morbidity and mortality. The mechanisms underlying delaying wound healing in diabetes are incompletely understood and tools to identify such pathways are eagerly awaited. Wound biopsies were obtained from 75 patients with diabetic foot ulcers. Matched subgroups of rapidly healing (RH, n = 17) and non-healing (NH, n = 11) patients were selected. Proteomic analysis was performed by labelling with isobaric tag for relative and… CONTINUE READING
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