The molecular mechanism of programmed cell death in C. elegans.

  title={The molecular mechanism of programmed cell death in C. elegans.},
  author={Qiong A. Liu and Michael O. Hengartner},
  journal={Annals of the New York Academy of Sciences},
Programmed cell death or apoptosis plays a fundamental role during animal development, metamorphosis, and tissue homeostasis. It is a genetically controlled physiological process that comprises two distinct and sequential processes: the death of cells, and their subsequent removal by engulfing cells. In the nematode C. elegans, genetic studies led to the discovery of 15 genes that function in programmed cell death (FIG. 1). These 15 genes have been divided into four groups based on the order of… CONTINUE READING


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