The molecular mechanism of action of artemisinin--the debate continues.

@article{Oneill2010TheMM,
  title={The molecular mechanism of action of artemisinin--the debate continues.},
  author={Paul M O'neill and Victoria E. Barton and Stephen A Ward},
  journal={Molecules},
  year={2010},
  volume={15 3},
  pages={1705-21}
}
Despite international efforts to 'roll back malaria' the 2008 World Malaria Report revealed the disease still affects approximately 3 billion people in 109 countries; 45 within the WHO African region. The latest report however does provide some 'cautious optimism'; more than one third of malarious countries have documented greater than 50% reductions in malaria cases in 2008 compared to 2000. The goal of the Member States at the World Health Assembly and 'Roll Back Malaria' (RBM) partnership is… CONTINUE READING

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Three-dimensional structure of Plasmodium falciparum Ca2+- ATPase(PfATP6) and docking of artemisinin derivatives to PfATP6

M. Jung, H. Kim, Y. N. Ki, T. N. Kyoung
Bioorg. Med. Chem. Lett. 2005, • 2010
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