The molecular mechanism of action of artemisinin--the debate continues.

  title={The molecular mechanism of action of artemisinin--the debate continues.},
  author={Paul M O'neill and Victoria E. Barton and Stephen A Ward},
  volume={15 3},
Despite international efforts to 'roll back malaria' the 2008 World Malaria Report revealed the disease still affects approximately 3 billion people in 109 countries; 45 within the WHO African region. The latest report however does provide some 'cautious optimism'; more than one third of malarious countries have documented greater than 50% reductions in malaria cases in 2008 compared to 2000. The goal of the Member States at the World Health Assembly and 'Roll Back Malaria' (RBM) partnership is… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 136 extracted citations


Publications referenced by this paper.
Showing 1-10 of 72 references

Three-dimensional structure of Plasmodium falciparum Ca2+- ATPase(PfATP6) and docking of artemisinin derivatives to PfATP6

M. Jung, H. Kim, Y. N. Ki, T. N. Kyoung
Bioorg. Med. Chem. Lett. 2005, • 2010
View 1 Excerpt

Similar Papers

Loading similar papers…