The molecular hallmarks of epigenetic control

@article{Allis2016TheMH,
  title={The molecular hallmarks of epigenetic control},
  author={C David Allis and Thomas Jenuwein},
  journal={Nature Reviews Genetics},
  year={2016},
  volume={17},
  pages={487-500}
}
Over the past 20 years, breakthrough discoveries of chromatin-modifying enzymes and associated mechanisms that alter chromatin in response to physiological or pathological signals have transformed our knowledge of epigenetics from a collection of curious biological phenomena to a functionally dissected research field. Here, we provide a personal perspective on the development of epigenetics, from its historical origins to what we define as 'the modern era of epigenetic research'. We primarily… CONTINUE READING

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