The molecular genetics of type-4 fimbriae in Pseudomonas aeruginosa--a review.

@article{Mattick1996TheMG,
  title={The molecular genetics of type-4 fimbriae in Pseudomonas aeruginosa--a review.},
  author={John S. Mattick and Cynthia B Whitchurch and Richard A. Alm},
  journal={Gene},
  year={1996},
  volume={179 1},
  pages={147-55}
}
Type-4 fimbriae (or pili) are filaments found at the poles of a wide range of bacterial pathogens, including Neisseria gonorrhoeae, Moraxella bovis, Dichelobacter nodosus and Pseudomonas aeruginosa. They are composed of a small subunit which is highly conserved among different species and appear to mediate adhesion and translocation across epithelial surfaces via a phenomenon termed "twitching motility'. These fimbriae are key host colonisation factors and important protective antigens. We have… CONTINUE READING

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