The molecular genetics of mitochondrial cytopathies: the Melbourne experience.

Abstract

Mitochondrial DNA is a unique, maternally inherited molecule encoding several subunits of the respiratory enzyme chain. In several mitochondrial cytopathies mutations have been described in this genome viz. large-scale heteroplasmic deletions in syndromes with progressive external ophthalmoplegia and point mutations in MELAS and MERRF encephalomyopathies… (More)

Topics

Cite this paper

@article{Thyagarajan1992TheMG, title={The molecular genetics of mitochondrial cytopathies: the Melbourne experience.}, author={Dominic Thyagarajan and Eileen Byrne and X Dennet and Sangkot Marzuki}, journal={Clinical and experimental neurology}, year={1992}, volume={29}, pages={172-81} }