The molecular genetics of human sex determination

  title={The molecular genetics of human sex determination},
  author={Ulrich Wolf},
  journal={Journal of Molecular Medicine},
The classical conception of the chromosomal mechanism of sex determination presumes a chromosome unique for and determining the heterogametic sex. On the basis of recent evidence, however, this picture is becoming increasingly complex, with a multitude of genes appearing to interact simultaneously or successively to bring about the gonadal phenotype. The genes identified so far that are thought to be involved in the process of human sex determination are distributed on various chromosomes, but… CONTINUE READING