The molecular epidemiology of hepatitis B in the Indigenous people of northern Australia

@article{Davies2013TheME,
  title={The molecular epidemiology of hepatitis B in the Indigenous people of northern Australia},
  author={Jane Davies and Margaret Littlejohn and Stephen Locarnini and Sarah E. Whiting and Krispin M Hajkowicz and Benjamin C Cowie and David Scott Bowden and Steven Y. C. Tong and Joshua S. Davis},
  journal={Journal of Gastroenterology and Hepatology},
  year={2013},
  volume={28}
}
The hepatitis B surface antigen was first described in the blood of an Indigenous Australian man, yet little is known about its molecular epidemiology in this population, in which it is endemic. The study aimed to determine the clinical and molecular epidemiology of hepatitis B virus (HBV) in Indigenous people from northern Australia. 
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42 Citations
Background Citations
15
Methods Citations
2

42 Citations

Citation Type

Citation Type

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Aboriginal and Torres Strait Islander people are disproportionately affected by hepatitis B virus (HBV) infection. A proposed mismatch between standard vaccines and the HBV/C4 sub‐genotype prevalent…
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HBsAg positivity is high in the NT, particularly in the Indigenous population, but a substantial part of this decrease is due to factors other than the universal vaccination program.
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TLDR
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TLDR
The HBV C4 variant found in this population has a high potential to cause advanced liver disease and to escape vaccination programs.
Molecular characterisation of hepatitis B virus isolated from human immunodeficiency virus-infected adults at various time points after the initiation of antiretroviral therapy
Dissertation submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, in fulfillment of the requirements for the degree of Master of Science in Medicine November…
Hepatitis B virus epidemiology.
TLDR
The increased recognition of HBV infection as a leading cause of death globally has resulted in the development of new structures and policies at the international level; immediate attention to implementing these strategies is now required.
Point of care and oral fluid hepatitis B testing in remote Indigenous communities of northern Australia
TLDR
The venous blood point of care test (POCT) or oral fluid laboratory test could be used to identify individuals with chronic HBV infection in high prevalence communities with limited access to health care.
Hepatitis B virus and human T-cell lymphotropic virus type 1 co-infection in the Northern Territory, Australia.
  • I. Marr, J. Davies, R. Baird
  • Medicine, Biology
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
  • 2017
Hepatitis B Virus Genotypes
TLDR
Hepatitis B virus (HBV) was discovered as the “Australian antigen” by Blumberg et al. in 1965 and was awarded the Nobel Prize for Physiology and Medicine in 1976.
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