The molecular epidemiology and phylogeography of Trypanosoma cruzi and parallel research on Leishmania: looking back and to the future.

@article{Miles2009TheME,
  title={The molecular epidemiology and phylogeography of Trypanosoma cruzi and parallel research on Leishmania: looking back and to the future.},
  author={Michael Alexander Miles and Martin Stephen Llewellyn and Michael David Lewis and Matthew Sze-Wei Yeo and Rania M. H. Baleela and Sinead Fitzpatrick and Michael W. Gaunt and Isabel L. Mauricio},
  journal={Parasitology},
  year={2009},
  volume={136 12},
  pages={1509-28}
}
Trypanosoma cruzi is the protozoan agent of Chagas disease, and the most important parasitic disease in Latin America. Protozoa of the genus Leishmania are global agents of visceral and cutaneous leishmaniasis, fatal and disfiguring diseases. In the 1970s multilocus enzyme electrophoresis demonstrated that T. cruzi is a heterogeneous complex. Six zymodemes were described, corresponding with currently recognized lineages, TcI and TcIIa-e--now defined by multiple genetic markers. Molecular… CONTINUE READING

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