The molecular cloning and identification of a gene product specifically required for nuclear movement in Aspergillus nidulans

@article{Osmani1990TheMC,
  title={The molecular cloning and identification of a gene product specifically required for nuclear movement in Aspergillus nidulans},
  author={Aysha H. Osmani and Stephen A Osmani and N. Ronald Morris},
  journal={The Journal of Cell Biology},
  year={1990},
  volume={111},
  pages={543 - 551}
}
A temperature-sensitive mutation in the nudC gene (nudC3) of Aspergillus nidulans specifically prevents the microtubule-based movement of nuclei in this organism at the restrictive temperature. The mutation does not affect short term growth, nuclear division, or the movement of other subcellular organelles. Immunofluorescence analysis of cells blocked at the restrictive temperature, using antitubulin antibodies, shows that the inability of nuclei to move under these conditions is not related to… CONTINUE READING