The molecular biology of vestibular schwannomas: dissecting the pathogenic process at the molecular level.

@article{Neff2006TheMB,
  title={The molecular biology of vestibular schwannomas: dissecting the pathogenic process at the molecular level.},
  author={Brian A. Neff and D Bradley Welling and Elena M. Akhmametyeva and L S Chang},
  journal={Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology},
  year={2006},
  volume={27 2},
  pages={197-208}
}
OBJECTIVE The goal of this article was to review concisely what is currently known about the tumorigenesis of vestibular schwannomas. BACKGROUND Recent advances in molecular biology have led to a better understanding of the cause of vestibular schwannomas. Mutations in the neurofibromatosis type 2 tumor suppressor gene (NF2) have been identified in these tumors. In addition, the interactions of merlin, the protein product of the NF2 gene, and other cellular proteins are beginning to give us a… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Spontaneous shrinkage of vestibular schwannoma

Surgical neurology international • 2016
View 1 Excerpt

Similar Papers

Loading similar papers…