The molecular biology of ependymomas.

  title={The molecular biology of ependymomas.},
  author={Ronald L. Hamilton and Ian F Pollack},
  journal={Brain pathology},
  volume={7 2},
Intracranial ependymomas are the third most common primary brain tumor in the pediatric population. Although an anaplastic variant is recognized, numerous studies examining the prognostic implications of histological features, such as necrosis, endothelial proliferation and mitoses, have yielded contradictory results. In order to improve outcome prediction in affected patients and to refine therapeutic decision-making, there is a strong need for identifying relevant biological correlates of… CONTINUE READING

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