The molecular biology of IRBP: application to problems of uveitis, protein chemistry, and evolution.

@article{Nickerson1991TheMB,
  title={The molecular biology of IRBP: application to problems of uveitis, protein chemistry, and evolution.},
  author={John M. Nickerson and Diane E Borst and T Michael Redmond and J S Si and Judith L. Toffenetti and Gerald J. Chader},
  journal={Progress in clinical and biological research},
  year={1991},
  volume={362},
  pages={139-61}
}
In closing, molecular biology has helped us in the study of uveitis, in defining the parts of the IRBP molecule that cause EAU/EAP. Simple northern and Southern blotting experiments can answer significant questions in the study of gene structure and expression and in relating these to genetic eye diseases. Molecular biology has provided answers to several long-standing cell biology question such as: where is IRBP synthesized, where is the gene expressed, and how is the IRBP polypeptide… CONTINUE READING

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