The molecular basis of sperm-oocyte membrane interactions during mammalian fertilization.


Gamete membrane interactions begin with adhesion (binding) of the sperm to the oocyte plasma membrane and culminate with fusion of the membranes of the gametes, thus creating the zygote through the union of these two very different cells. This review summarizes the molecular and cell biology of the cell-cell interactions between mammalian gametes. Recent… (More)


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