The mode of action of the Bacillus thuringiensis vegetative insecticidal protein Vip3A differs from that of Cry1Ab delta-endotoxin.

@article{Lee2003TheMO,
  title={The mode of action of the Bacillus thuringiensis vegetative insecticidal protein Vip3A differs from that of Cry1Ab delta-endotoxin.},
  author={Mi Kyong Lee and Frederick S. Walters and Hope Hart and Narendra V Palekar and Jingdong Chen},
  journal={Applied and environmental microbiology},
  year={2003},
  volume={69 8},
  pages={
          4648-57
        }
}
The Vip3A protein, secreted by Bacillus spp. during the vegetative stage of growth, represents a new family of insecticidal proteins. In our investigation of the mode of action of Vip3A, the 88-kDa Vip3A full-length toxin (Vip3A-F) was proteolytically activated to an approximately 62-kDa core toxin either by trypsin (Vip3A-T) or lepidopteran gut juice extracts (Vip3A-G). Biotinylated Vip3A-G demonstrated competitive binding to lepidopteran midgut brush border membrane vesicles (BBMV… CONTINUE READING
Highly Influential
This paper has highly influenced 17 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Highly Cited
This paper has 107 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 68 extracted citations

Vip3Aa induces apoptosis in cultured Spodoptera frugiperda (Sf9) cells.

Toxicon : official journal of the International Society on Toxinology • 2016
View 12 Excerpts
Highly Influenced

Proteolytic activation of Bacillus thuringiensis Vip3Aa protein by Spodoptera exigua midgut protease.

International journal of biological macromolecules • 2018
View 4 Excerpts
Highly Influenced

108 Citations

051015'07'10'13'16'19
Citations per Year
Semantic Scholar estimates that this publication has 108 citations based on the available data.

See our FAQ for additional information.