The mode of action of taxol: apoptosis at low concentration and necrosis at high concentration.

Abstract

The cytotoxicity of Taxol represents both inhibition of cell proliferation and cell death. The drug blocked cells in the G2/M phase of the cell cycle. It has also been reported that Taxol induced cell apoptosis; however, the mode of action of Taxol is far from clear. In this communication, the cytotoxicity of Taxol in various breast cancer cell lines was… (More)

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Cite this paper

@article{Yeung1999TheMO, title={The mode of action of taxol: apoptosis at low concentration and necrosis at high concentration.}, author={T. K. Yeung and Charlotte Germond and X. Chen and Zhehui Wang}, journal={Biochemical and biophysical research communications}, year={1999}, volume={263 2}, pages={398-404} }