The mode of action of SA-FF22, a lantibiotic isolated from Streptococcus pyogenes strain FF22.

@article{Jack1994TheMO,
  title={The mode of action of SA-FF22, a lantibiotic isolated from Streptococcus pyogenes strain FF22.},
  author={Robert Smail Jack and Roland Benz and John Robert Tagg and Hans Georg Sahl},
  journal={European journal of biochemistry},
  year={1994},
  volume={219 1-2},
  pages={699-705}
}
SA-FF22 is a lanthionine-containing bacteriocidal peptide isolated from Streptococcus pyogenes strain FF22. The peptide interacts closely with non-energised artificial phospholipid vesicles, as evidenced by a 'blue shift' in the fluorescent emissions associated with a tryptophan residue within the peptide sequence. Furthermore, SA-FF22 induced efflux of… CONTINUE READING