The mitogenic activity of OKT3 and anti-Leu 4 monoclonal antibodies: a comparative study.

Abstract

The mitogenic properties of OKT3 (IgG2a) and anti-Leu 4 (IgG1), two monoclonal antibodies directed at the same surface antigen of human T cells, have been studied. Both antibodies, at subnanomolar concentrations, induced thymidine incorporation of comparable magnitude into human peripheral blood mononuclear cell cultures. Their mitogenicity reached peak… (More)

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Cite this paper

@article{Wauwe1983TheMA, title={The mitogenic activity of OKT3 and anti-Leu 4 monoclonal antibodies: a comparative study.}, author={Jean P Van Wauwe and Joris Goossens}, journal={Cellular immunology}, year={1983}, volume={77 1}, pages={23-9} }