The mitochondrial ADP/ATP carrier: functional and structural studies in the route of elucidating pathophysiological aspects.

@article{Trzguet2008TheMA,
  title={The mitochondrial ADP/ATP carrier: functional and structural studies in the route of elucidating pathophysiological aspects.},
  author={V{\'e}ronique Tr{\'e}z{\'e}guet and Ludovic P{\'e}losi and Guy J-M Lauquin and G{\'e}rard Brandolin},
  journal={Journal of bioenergetics and biomembranes},
  year={2008},
  volume={40 5},
  pages={435-43}
}
The mitochondrial ADP/ATP carrier plays a central role in aerobic cell energetics by providing to the cytosol the ATP generated by oxidative phosphorylation. Though discovered around 40 years ago owing to the existence of unique inhibitors and in spite of numerous experimental approaches, this carrier, which stands as a model of the mitochondrial solute… CONTINUE READING