The migration of Ascaris suum larvae, and the associated pulmonary inflammatory response in susceptible C57BL/6j and resistant CBA/Ca mice.

@article{Lewis2007TheMO,
  title={The migration of Ascaris suum larvae, and the associated pulmonary inflammatory response in susceptible C57BL/6j and resistant CBA/Ca mice.},
  author={Ramsey Lewis and Jerzy M Behnke and Joseph P. Cassidy and Peter G Stafford and N C Murray and Celia V. Holland},
  journal={Parasitology},
  year={2007},
  volume={134 Pt 9},
  pages={1301-14}
}
Ascariasis is an important infection in humans (Ascaris lumbricoides) and pigs (Ascaris suum) and individuals appear to be predisposed to either heavy or light worm burdens. These extremes of susceptibility and resistance are represented in a mouse model by 2 strains of mice, CBA mice showing high resistance to infection and C57BL/6 which are highly susceptible, as reflected in worm burdens in the lungs 6-7 days after infection. In an attempt to identify the point at which the difference… CONTINUE READING